1 Subgroup 3 . Eye Irritation
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چکیده
منابع مشابه
Effects of photochemical air pollution on the human eye--concerning eye irritation, tear lysozyme and tear pH.
This paper is presented to make both ocular symptoms and signs clear, by means of some experiments on the eye affected by photochemical air pollution. This paper summarizes three experiments, these results and discussion. The first series of experiments were performed in order to research eye irritation caused by photochemical synthetic irritants. They proved the threshold of eye irritation and...
متن کاملInter-laboratory study of short time exposure (STE) test for predicting eye irritation potential of chemicals and correspondence to globally harmonized system (GHS) classification.
Short time exposure (STE) test using rabbit corneal cell line (SIRC) cells was developed as an alternative eye irritation test. STE test uses relative viability as the endpoint after cells are exposed to the test material at constant concentrations for 5 min. In this inter-laboratory study with 3 laboratories, 44 chemicals with a wide range of classes were evaluated for the transferability, bet...
متن کاملUpdate on the Colipa research programme for development of in vitro alternative methods for eye irritation
The COLIPA eye irritation programme for development of in vitro eye irritation assays incorporates integrated research projects and collaborative activities with external partners. The research projects focus on understanding mechanisms of eye injury and identification of new in vitro endpoints more predictive of the in vivo human response to chemical injury resulting in new or improved in vitr...
متن کاملTiO2 Nanoparticles as a Common Component of Sunscreens: An Experimental Study of Dermal/Ocular Safety Assessment
Background: The safety evaluations of sunscreens containing Titanium Dioxide-Nanoparticles (TiO2-NPs) were done by dermal exposure, acute dermal and eye irritation/corrosion, and skin sensitization according to the guideline for Organization for Economic Co-operation and Development (OECD). OBJECTIVES: The aim of our study was the evaluation of safety and toxicity of TiO2-NPs following acute su...
متن کاملAssociation between high tear epidermal growth factor levels and corneal subepithelial fibrosis in dry eye conditions.
PURPOSE To compare tear epidermal growth factor (EGF) concentration in dry eye (DE) conditions and determine correlations between EGF levels and severity of symptoms and ocular surface signs. METHODS In this prospective case-control study, 35 patients with DE, including subgroups with meibomian gland disease (MGD), Sjögren's syndrome (SS) aqueous tear deficiency, or neurotrophic keratopathy (...
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